SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38050d6a6ba8bab0ac66d4227f79734aad4f48eb3031c1528b50e6541621abd5' 
  AND token = 'ewNT7ly4K1wi/EAaJf3j1YI7Y+J3jmDAGFjmYoorX1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}