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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd0e530b67c6d164a352d4aafc22d0c44b7eba3291d5d643a84c91da83a133c1' 
  AND token = 'NxvWxTIdEss2TCuKgMjL44HBZdVAzeh+yusIlWx0Z/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}