SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4126e98f713ad2a2a38f07e4e4cad0fd9264b517b7d01517a51587f470f52e35' 
  AND token = 'JziacNMSlEWuNaYJVlzM4UI/XmXoQgib7jQsDxFj3dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}