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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a5a7d3fc861f508724d3d8b78c68e929bc9f8673283189a3483349067a3d2d' 
  AND token = '2Csw4CTU8W8g/YM/M+nZCq3DYZRGmfH9EU89khNK918=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}