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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a35691d9e573225df68f0f551ad394299da99c9af5e501c86dfbe065e1acfa6' 
  AND token = 'UpVtvwh0Fx64UTOqOX05QyEZU9XlpA9IXeiG9kYooQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}