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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ab53c0afb216f226f09bb0b701a2c8398a8a79591b5766c603cf4571138bf20' 
  AND token = 'uqkv8FtuOJAd2ttf1pABk8+v55mSbMqKEY0ZnAY6p50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}