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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5422acdb2e42948e7fc4dcfb51203902a9cb8e10de3b6264b53384dd92c7ac5a' 
  AND token = 'QGIxW+UT3slEww3wjb1Cv0gCjIGNZTHjDSFNiNCE3iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}