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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a1212d167dad9bdb6bdb80aa4b1ebeead13ab95388da7de4ea6ad2d589f1ae' 
  AND token = 'qRMJlnSYwcIii8XeUYF/m2SlAH0EEx14W9hOgllG4aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}