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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05e48251587810357f3dbeb408fdfb74ce3ff4b6006a18ce78eb0e13237aadb' 
  AND token = 'Px9iKLs6uUVMrtt+F4779+DeiZY9HV1La1uH/PwiUd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}