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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177851628f06bd1c82ff4fb4d59601016b5bd76685320c4841f5b657f547d340' 
  AND token = 'ABpHy0zMpaLIjO9BqtB5w8zPhQB6eAZryAzhZCv7DUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}