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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d69895198dc57a99546799ccdd2e06afd0e84f3d3fbe2d72e7f2282de4bc3e2' 
  AND token = 'UCIxoY/+0HXBsNMOA7c7tD+VripACLDJK44pFDOC6Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}