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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cbfc6ad6ba45e4790cb3bca31d1aab269b891b55bbaae3702f1903341f3c2c' 
  AND token = '5ysm2YJXfNVKspy4uDLcQ17jkpwdK/+WW3DRRUOCIGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}