SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375eaf04d4d13f73e97d4e63b5438099aee89a2b27e1663eac3a180f30a5cfd6' 
  AND token = 'cStdEZlQiWKbFUxGW8nSdiizOKKOHhMRDf2L1wxyfdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}