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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7b2b5ccea3377f3b92647a6d9bff8b692919647b9a62b67ef5be82a07d474e' 
  AND token = 'TXWXIQBiyXRFNjgZAubWw5sKxf0FnJZ6ck1K3eojkDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}