SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3818b5759629ff8da0569cbf58ab013170565ee089f8c37988b22ca29287245' 
  AND token = 'SRQY7eONUgIyTgks8QEvaxTp0YY4212uqQmww9Mk6Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}