SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64fe683f059fd3b59558e0ff1b006c1d957f168e0c61b6882d4288ae9f59e429' 
  AND token = 'FIui/Z2lwnDOY1fgxYYYF4+oo2o03Uf+Fr9u5hi3rc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}