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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b380a6c91c47db6c4915ce4f608998991cc6425b897a3a7b4460138441de2f' 
  AND token = '1jr+A6wMsGfCKYN7czG/cPZoPQDJfNbza31bU1o+Ih8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}