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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4b5e81f28aca68d2e8ece6015e3f011dcd9005f39136f6cc1a62e0a257a339' 
  AND token = 'raNY+rmCeQflhCDDdm7l6BpbFqQoHy41cYpszndcQno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}