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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0b37393b136e02e75348240198131160ab6345e7849bac301ed6fb1e8f1d80' 
  AND token = 'awy+52dEvIxzv1SjsO3W9bWTjPfcPWL/25n0WDdwjio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}