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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac25741dd6de65f1bb8ef75764c4386459de5e2b6ad6d73e4bfbc6deeaef0bd3' 
  AND token = 'UUmasXQv4IpgjkVFlXTuq/MbATwYCElfcx3YsJea9uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}