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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64bbbbeeccd0f40f94a6795e8b6f2d741e59bbe51cf56d2cdcf78b34819e3ab' 
  AND token = 'U2ChPYosH+bbJ+OO6SvjvEJw0/Dp0nByUwajYjR8YSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}