SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83d7c1f951a5be47e2c8e740be366afcbb01c8be24dca6bca4c39e476f857593' 
  AND token = 'Rg4AGs5ONr0HXc6qCfUmDZKWH6b3bIZA5eOcy4UUyvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}