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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2cdd144af4dd5f597dfd84316d1e9a269c121a736569c786b2e749c09d4782' 
  AND token = 'dEFTRPpfN92k/B7lUFrAasW8dGPhkz69HjQyczNzCu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}