SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6b7483ee8a0d5c0533f71308a63a02316c3d45bc4ddb7cd263367793703955' 
  AND token = '+scaPOV2etxzJ06OWSiroEIo0UKM3mza2LpR9opH6rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}