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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4b8aa5e9a5383391a3de18788337b21458324bb9c55397704e7da1e5c16657' 
  AND token = 'uQEmfEpgH6etD682uKE3By4vRTJ7xteTN9Phepwn/2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}