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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344f2a0bbd538abc2fbce8e879353203794e966d722de47daeeae74358a52e06' 
  AND token = 'PotEaSn0xG+z6JoOevRYzWbSTVwP7jIYjqjSQl+PfDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}