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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fbd66a34af2865e90567463757db78ab08e1faa0beb79b2f858244e545b2b7' 
  AND token = 'GT6kgMem2MdWp5traOs2rEggXCrpMCv14o3HDFSKr/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}