SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63db330b81816a03f807288820e51f15442ad95abfb2441fd7a5e3c0e4ca203' 
  AND token = 'S7XDt35CO2CUa4UkJnmWZYrQLScWJLa06VskED0cTPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}