SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72955c13ceb9951304d565f944a5cf7ae015a99b64be1c9b6ffeb8057d2c2c1' 
  AND token = 'eEwM/1BM4pJm75Od7F0Ax4KXNZeZhNgKUmpN3sCGUEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00093

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}