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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f35306c242cc074bfc7b7a90deb12d50cc2dc92f23b4590f1d521765992e863' 
  AND token = '2UO4u3qSaSeHnWpreYSfOPHl6WXa5IgYxE/SweW0ttw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}