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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a9d03d31a2ef0a70b381c6fd201b89b077521d2acd7ebb5e90ecee77b78750' 
  AND token = 'IbtUOReSmq419qhSF6BrjDqXyHhA/Ol+r2Lry7/4ocs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}