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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4021999546913d670609736024085ead6fafdd6ac12e7fd90e7f6c384b75cd8d' 
  AND token = 'HGu1TJl9Vz1MlRXwB17EqoOTT9xNr6kQf6zxcJ7jiL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}