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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1949ae6be248d3ad8aae1b9a17eba7684af14c2fda84ceee35a72644645568e0' 
  AND token = 'EE8nscG0D+K5pPBdD1rIXev+Ih+Us4wJLbodrTlDNWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}