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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243d74cc66503e826a438ee9d1c646c329b2dacf2ad206d606cd99bd7cb4d762' 
  AND token = 'I1+2rd+472heaho9AydBvhV2jAeZUq6yKbs+FSSqbLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}