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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45cb0010cab89e34459f4d2105142143ad37fa007355eb9c70f7b44f006136f' 
  AND token = 'vWvJnK5fK581lFy5Jc8wHT/8Iuz7Bmn+z4CcDbXRRFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}