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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122c9c19c9155d179998d0d9c0b262dbc10c4f5f8f481022f0496fab243640ac' 
  AND token = 'X3l2jcjLjc2Mc9uWvNHttu5UB7GPlSEkxP5uifWeJwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}