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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7563ace839e75d2c52fe2560d4ab48bbca6021f59edba5b445c6234b83ba7d73' 
  AND token = 'iFuaz+LKJoQgeCew1QbjOrHyrlt+rXSO6PqmQsZ9SK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}