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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f6cf63216c4274c775ef1b5e63c104239a03e72d8bface052ee5a65e3d9c83' 
  AND token = 'gTk7WRPlqbqGaBSIU+nDt8aPzCXR9jtCMXU/CTMOfYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}