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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f50ed1f6374cc7b04ade670d781c29caa7b5c4384ec53f0ba691a2df09e873' 
  AND token = 'i7sp4j3NvGnSmcb4AsTKcUgYwfiAR7t7EZONncddmFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}