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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14640b1a487ddf8a38f48f06f89ec4f41cb29e012aeeb005df2ff1e13fa72ee' 
  AND token = 'K0o/ZqtDpxooVEoxSySK+iXq7bqaxcHQrp33eG3YDoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}