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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0253589b3f3b37e9d2b8523972ca5916ea84ac055b2fdfa10d61704ca410a1da' 
  AND token = 'GR/jx8UI7pM8RdP/rzHD2Iuacdc1t1QfN1aFRjPqLAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}