SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1422d1902c75f44a56f738594ff3a53983e09abda8ff7072eb2f6c44b7282060' 
  AND token = 'w73irJH1hFoPGT6L1K6ovc/gDl7hZRlfeWolc7GPyVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}