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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dbdeb542237bef9aa140aba0f8a25aadb2e26ff7076b49ed38ac8c550aca389' 
  AND token = 'MwLUiwGVuEpuHKwjbK+eMvG9psQOCVTAWVwWxL8CO6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}