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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '655d1d66d372eeb4dce5bb5ae304d107f96ed9b740a259c5224bf078a40670af' 
  AND token = 'HLdt6YiUAJgVp5tej5tyZ3TuUsqq52+9WV6OHjDCBW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}