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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adad447b64667fb6c72bd0d27012eed60f98deb80c435a34fe05978aed8f3b4' 
  AND token = '75b0njxFt8NEns1D0QUevxNiGKwCvsr1YBMWLZw6zaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}