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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22aa643c1c1b5dc16bfa118697a585b81e13b16a226b38eb4362fb8fa0ec6afe' 
  AND token = 'yd6E6YGm6363BLBBOR+cIGJYThcI6RlxjWEOnOyJ16Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}