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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df6b959c535bcbb35024123e32aec153f2680e820cb8e0f8cf43d2c58f8e131' 
  AND token = '86hMgbbQewy+MC09wjsfstK6N72Pvm4JzbRwoE7HRM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}