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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50f09e533ba96d8ebdb9b6ecce4e53a47d942cfcad825757716a02c6886bed6' 
  AND token = 'Au3wwvkkTEu1q4J2OFK3f6N5mIXEYLwJbmZ/DU0gLmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}