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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c53981e8edf4074d9bc0f0589e0e3f957607a368a602facfb367c57d032bdd3' 
  AND token = '5wZ0smvDnqNk8L7VHH8bzcESGMU2gTqJy/Vb3bVs3x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}