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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e00af9b740854f850c16460459f2a1c4a79d2184767419ee7a9f1a94e6e3c1f4' 
  AND token = 'jZaLV/cuRhUfzhETtLgd5+me3j/2t4XpATLgXzQySbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}